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Preceptors:
Earl G. Siegel, PharmD....................................................513-636-5053
Robert J. Goetz, PharmD, DABAT...................................513-636-5061
This course requires varying degrees of independent work. Many factors will contribute to the availability, content, and specifics of this course at any certain time.
GOAL:
The goal of the Toxicology Rotation is to provide the Resident with an experiential, interactive and didactic background in the pathophysiology and management in the acutely and chronically poisoned adult and pediatric patients.
COMPETENCIES:
A resident who completes a one-month rotation in Toxicology shall be able to:
- Effectively communicate with all members of the health care team both to Elicit and disseminate information.
- Develop clinical skills in the diagnosis and treatment of acute and chronic poisoning in adults and children on both the inpatient and outpatient basis.
- Demonstrates knowledge of environmental and occupational toxicology.
- Demonstrate knowledge of NIOSH, OSHA, EPA and other agencies concerned with monitoring toxins in the community.
- Demonstrate an understanding of the following overdose or exposures and their acute therapy.
- acetaminophen
- alcohols – ethanol, methanol, isopropyl , ethylene glycol
- amphetamines, MDMA
- benzodiazepines
- beta blockers
- barbiturates
- calcium channel blockers
- cardiac glycosides
- chloral hydrate
- cocaine
- ethclorvynol
- glutethmide
- narcotics
- nonprescription stimulants
- phenothiazines
- salicylates
- vitamins
- tobacco
- tricyclic antidepressants
- atypical antipsychotics
- hydrofluoric acid
- Degreaser’s Flush
- Metal Fume Fever
- caustics
- warfarin type rodenticides
- pesticides
- cyanoacrylates
- camphor
- boric acid
- naphthalene
- paradichlorobenzene
- propoxyphene
- insecticides
- iron
- petroleum distillates/hydrocarbons
- household plants
- nerve agents
- bioterrorism
- substance abuse
- carbon monoxide
- isocyanates
- household cleaning agents
- ethylene glycol
- lead
- androgenic steroids
- arsenic
- mercury
- weapons of mass destruction
- Compare and contrast the various means of gastrointestinal decontamination.
- Recite and explain the mechanisms, use, dose and dangers of the available antidotes used in toxicology (including FAB fragments, flumazenil, hyperbaric oxygen (HBO) and others.
- Demonstrate an understanding and familiarity of the various specialized sources of information pertinent to toxicology.
- Demonstrate an ability to communicate effectively on the DPIC lines and to incorporate psychosocial aspects and hidden agenda into effective over the telephone management of emergency toxicology cases.
- Prepare and present a topic of interest in the area of “pharmacology and toxicology.”
III. FACILITIES TO BE USED
- Department of Emergency Medicine, University Hospital
- Department of Emergency Medicine, Children’s Hospital
- Occupational Toxicology
- Clinical Studies
- Occupational Health Clinic
- Toxicology Laboratory of University Hospital (lab one)
- Coroner’s Office, EPA, NIOSH
- Drug & Poison Information Center
IV. READING LIST
Student will be responsible for information in DPIC Micromedex and major toxicology references that relate to items in II. E.
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